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Title:
A Kupffer-sejtek szerepe a máj gyulladásos és metabolikus folyamatainak szabályozásában - Irodalmi áttekintés
dc.contributor.authorMátis, Gábor
dc.contributor.authorHatala, Patrícia
dc.contributor.authorKulcsár, Anna
dc.contributor.authorKulcsárné Petrilla, Janka
dc.contributor.authorNeogrády, Zsuzsanna
dc.date.accessioned2021-05-12T08:35:08Z
dc.date.available2021-05-12T08:35:08Z
dc.date.issued2015-09
dc.identifier.citationMagyar Állatorvosok Lapja 137(9), 569-575. (2015)en_US
dc.identifier.urihttp://hdl.handle.net/10832/2980
dc.description.abstractSUMMARY Based on literature data, the authors present the central role of Kupffer cells as resident liver macrophages in the regulation of hepatic inflammatory response and metabolic processes. Lipopolysaccharide (LPS) type endotoxins originated from Gram negative bacteria causing enteric infections, may trigger inflammation in the liver via the mediation of Kupffer cells, which is of special importance in the veterinary medicine, as well. Kupffer cells are being activated by binding LPS to cell surface receptors, stimulating pro-inflammatory cytokine, eicosanoid and chemokine production, thus regulating the systemic immune response. The authors showed that according to recent studies, the function of Kupffer cells could be affected by alterations of lipid homeostasis, and Kupffer cells are playing pivotal role in the pathogenesis of hepatic lipidosis. Furthermore, Kupffer cells are highly involved in the complex regulation of metabolic processes, being potent effectors of insulin sensitivity, carbohydrate and lipid metabolism as key cells in immunometabolic interactions.en_US
dc.language.isohuen_US
dc.publisherMagyar Állatorvosok Lapjaen_US
dc.titleA Kupffer-sejtek szerepe a máj gyulladásos és metabolikus folyamatainak szabályozásában - Irodalmi áttekintésen_US
dc.title.alternativeRole of Kupffer-cells in the regulation of hepatic inflammatory and metabolic processes - Literature reviewen_US
dc.typeArticleen_US
dcterms.bibliographicCitationMagyar Állatorvosok Lapja 137(9), 569-575. (2015)


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