Hungarian Veterinary Archive

HomeCollectionsKnowledge baseSearch/BrowseConnection
JavaScript is disabled for your browser. Some features of this site may not work without it.
Title:
Kutyák előesett harmadik szemhéj mirigyének kórszövettani és pancytokeratin-, ill. E-cadherin alapú immunhisztokémiai vizsgálata
Author:
Dobos, András
Varsányi, Balázs
Jakab, Csaba
Date:
2018-10
Abstract:
SUMMARY Background: Prolapse of the third eyelid gland is the most common primary disorder of the canine nictitating membrane. Objectives: The aim of the present histopathological, immunohistochemical study was to describe microscopic pathomorphological lesions of the parenchyma, and the interstitium of the surgically removed prolapsed canine third eyelid glands (TEG), compared to the normal ones. Materials and Methods: Five intact, and 26 surgically removed prolapsed TEG samples were separated and conserved in buffered, 8% formalin for 24 hours at room temperature, embedded in paraffin wax and further processed for sectioning (3–4 µm) and immunohistochemistry (antibodies: anti-pancytokeratin, and anti-E-cadherine). Results and Discussion: Histopathological lesions included (n = 26): 53.84% (n = 14) acute purulent parenchymatous adenitis, which was accompanied by with acute purulent ductal inflammation in 9 cases; 34.61% (n = 9) subacute-chronic lymphocytic interstitial adenitis, coupled with acinar degeneration and necrosis in 8 cases; 30.77% (n = 8) interstitial fibrosis; 3.85% (n = 1) adenoma. During the immunohistochemical investigations, the inflamed, degenerated TEG showed weaker or even loss of the pancytokeratin-, and E-cadherine-expression.
URI:
http://hdl.handle.net/10832/2791
MAL 2018 10 613 (3.626Mb)
Share:
gffdg
Share on Google+
Show full item record

 

 

magyarenglish

Search

Go to advanced search

Login

Open Archives InitiativeMagyar Tudományos Művek Tára